EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

HEPATITIS C. VIRAL INFECTION IN PATIENTS WITH NON-HODGKIN LYMPHOMA

*Khldoun Salah Aslan

ABSTRACT

Background: Lymphoma is considered a serious disease with an increased prevalence , so it was necessary to research all its possible causes, including HCV infection, to search for new treatments and prevention methods. This study is the first of its kind in Syria to investigate the relationship between HCV infection and the occurrence of lymphoma,. Numerous studies have proven that the correct treatment of HCV infection in patients with some types of lymphoma significantly improves the prognosis and therefore the detection and treatment of HCV is extremely important. The aim of the study: Measurement of the level of HCV antibodies in patients with non-Hodgkin Lymphoma and comparison with two groups (healthy people, patients with solid tumors) in order to study the possible relationship between Hepatitis C and lymphoma. Materials and Methods: This study was conducted at Tishreen University Hospital, Syria between 2023-2024. Serological samples were collected for three groups: the first group consists of 58 patients with all types of non-Hodgkin lymphoma, the second group consists patients with solid tumors (64 patients), and the third healthy group (61 people). After separated the hematogram using a micropipette and transferred it to the Eppendorf tubes, Direct ELISA technique was used to detect anti HCV IgG. Results: The study sample included 58 patients, 50 patients were negative in hepatitis C Virus Antibodies ( 86.2%) , while the number of positive patients were 8 patients by (13.8%). We can say that there is an association between Hepatitis C infection and non- Hodgkin lymphoma, but we cannot say for sure that HCV infection will inevitably lead to non- Hodgkin Lymphoma.

Keywords: Non-Hodgkin Lymphoma, Hepatitis HCV, ELISA, Antibodies.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia