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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57



*Marah Ali, Youssef Youssef and Mostafa Ibrahim


Objective: To identify antecedent risk factors for predicting vocal cord leukoplakia recurrence and malignant transformation. Materials and methods: The sample included 58 patients attending the Ear, Nose, and Throat Surgery Clinic at Tishreen University Hospital during the time period 2022-2023 with white lesions on the vocal cord and who met the inclusion criteria in the research. Their ages ranged from 35 to 77 years, with an average of 64.27 ± 6.8 years. All patients participating in the study were interviewed and the following information was recorded for each patient: name; Age, gender, habits and instincts (smoker, alcoholic); Then he took a comprehensive medical history from the patients, A comprehensive clinical examination of the head and neck was performed and the larynx was carefully examined with a laryngoscope. The morphological features of the lesion and its extension on the vocal cord were recorded. An initial clinical diagnosis was made. Then a tissue biopsy of the white lesion on the vocal cord was performed and sent to the pathological autopsy. After the results appeared, appropriate treatment), patients were monitored for 18 months, during which factors leading to leukoplakia recurrence and transformation into malignancy were identified. Results: The study showed that the smoking and the degree of dysplasia and the extent of the lesion extending over the vocal cord have a significant statistical significance in the recurrence of vocal cord leukoplakia and its transformation into malignancy. Conclusions: The patient should be informed of the possibility of leukoplakia reoccurring and becoming malignant if the patient is a smoker, and/or has vocal cord leukoplakia with a lesion of more than half of the vocal cord and/or moderate or severe dysplasia on histological biopsy result.

Keywords: Pathology of laryngeal cancer, recurrence of vocal cord leukoplakia.

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia