NANOSPONGES- A POTENTIAL NANOCARRIER: A REVIEW

Yashasvi*, A. R. Shabaraya, Deekshitha

ABSTRACT

The development of a targeted drug delivery system has been made possible by recent developments in nanotechnology. To successfully target a molecule to a specific site using a drug delivery system, however, a specialized drug delivery system is required. The development of nanosponge has become an essential step in resolving concerns related to drug toxicity, limited bioavailability, and predictable drug release since they can accommodate both hydrophilic and hydrophobic medicines. Nanosponges has a unique ability to trap drug moieties and offer the benefit of desired release due to their porous structure. Nanosponges are microscopic sponges that may adhere to surfaces and move throughout the body to target locations in order to deliver medications in a controlled and predictable manner. Another important character of these sponges is their aqueous solubility; this allows the use of these systems effectively for drugs with poor solubility. Utilizing crosslinkers to link the polymer, nanosponges can be created. The distribution of oral and topical drugs has been the subject of much research on nanosponge technology. This review focuses on the general overview of nanosponge, their manufacturing method, characterization, and their application in drug delivery systems.

Keywords: Nanosponges, Targeted drug delivery, Polymer, Poor solubility.