A CLINICAL RESEARCH ON THE COMBINED EFFECT OF KOLADI UPANAHA SWEDA AND ADITYAPAKA GUGGULU IN THE MANAGEMENT OF JANU SANDHIGATAVA VIS-A-VIS OSTEOARTHRITIS OF KNEE JOINT

Nimmi M. Menon* and Manjunath Adiga

ABSTRACT

Background: Sandhigata Vata is one of the most common Vatavyadhi and based on the clinical features it can be correlated to Osteoarthritis mentioned in the contemporary science. Being a chronic, degenerative inflammatory disease of the knee joint; it causes huge hindrance in the day to day activities of an individual. In this clinical study, total 30 patients having the complaints of Janu Sandhigata Vata (Osteoarthritis of Knee joint) were selected and intervened with Koladi Upanaha Sweda externally and Adityapaka Guggulu orally. Objective: To evaluate the combined therapeutic effects of Koladi Upanaha Sweda and Adityapaka Guggulu in the management of Janu Sandhigata Vata vis-a-vis to Osteoarthritis of Knee Joint. Materials and Methods: Koladi Upanaha Sweda externally for 7 days and internal administration of Adityapaka Guggulu in the dose of 1gm i.e., 500mg two tablets thrice a day (in the morning, afternoon and at night) with lukewarm water as Anupana after food for 14 days. The total study was intervened for duration of 21 days. The patients were assessed based on WOMAC index (Western Ontario and McMaster University Osteoarthritis index) and the Lakshanas of Janu Sandhigata Vata before, mid, after the treatment & on follow up respectively. Observation & Results: Clinical data was collected and analyzed statistically. For subjective parameters, Wilcoxon signed rank test was used to compare the mean rank within the group, and for objective parameters, students paired‘t’-test was used to compare the mean value within the group. Interpretation & Conclusion: The study showed that the combined efficacy of the interventions found to be more efficacious and showed statistically highly significant results in relieving the symptoms.

Keywords: Janu Sandhigata Vata, Osteoarthritis, Vata Vyadhi, Koladi Upanaha Sweda, Adityapaka Guggulu, Upanaha sweda.