EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

A CLINICAL RESEARCH ON THE COMBINED EFFECT OF KOLADI UPANAHA SWEDA AND ADITYAPAKA GUGGULU IN THE MANAGEMENT OF JANU SANDHIGATAVA VIS-A-VIS OSTEOARTHRITIS OF KNEE JOINT

Nimmi M. Menon* and Manjunath Adiga

ABSTRACT

Background: Sandhigata Vata is one of the most common Vatavyadhi and based on the clinical features it can be correlated to Osteoarthritis mentioned in the contemporary science. Being a chronic, degenerative inflammatory disease of the knee joint; it causes huge hindrance in the day to day activities of an individual. In this clinical study, total 30 patients having the complaints of Janu Sandhigata Vata (Osteoarthritis of Knee joint) were selected and intervened with Koladi Upanaha Sweda externally and Adityapaka Guggulu orally. Objective: To evaluate the combined therapeutic effects of Koladi Upanaha Sweda and Adityapaka Guggulu in the management of Janu Sandhigata Vata vis-a-vis to Osteoarthritis of Knee Joint. Materials and Methods: Koladi Upanaha Sweda externally for 7 days and internal administration of Adityapaka Guggulu in the dose of 1gm i.e., 500mg two tablets thrice a day (in the morning, afternoon and at night) with lukewarm water as Anupana after food for 14 days. The total study was intervened for duration of 21 days. The patients were assessed based on WOMAC index (Western Ontario and McMaster University Osteoarthritis index) and the Lakshanas of Janu Sandhigata Vata before, mid, after the treatment & on follow up respectively. Observation & Results: Clinical data was collected and analyzed statistically. For subjective parameters, Wilcoxon signed rank test was used to compare the mean rank within the group, and for objective parameters, students paired‘t’-test was used to compare the mean value within the group. Interpretation & Conclusion: The study showed that the combined efficacy of the interventions found to be more efficacious and showed statistically highly significant results in relieving the symptoms.

Keywords: Janu Sandhigata Vata, Osteoarthritis, Vata Vyadhi, Koladi Upanaha Sweda, Adityapaka Guggulu, Upanaha sweda.

[Full Text Article] [Download Certificate]