EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

PROTECTIVE EFFECTS OF ICARIIN ON CARDIOVASCULAR DISEASES – A REVIEW

Shabrina Zahratun Nisa, Adella Marsyanti, Aulia Nursyifa, Dhea Ananda, Diana Karlina,
Dini Hakiki, Fitrah Nur Fitriani, Lutvia Ramadhina, Muhammad Rizki Aditya, Nihal Shahifah,
Putri Fitriyah Husnul Khotimah, Rifky Syarif, Ristin Prasmawati, Rizma Septia Wahyuningsih,
Tarradiva Rosita Fitri, and Maulana Yusuf Alkandahri*

ABSTRACT

When the function of the heart and blood vessels is obstructed, cardiovascular disease is the resulting condition. Researchers have identified Icariin, a bioactive flavonoid compound from the genus Epimedium, as having a protective effect against a range of cardiovascular diseases. As a prenylated flavonol glycoside, this substance is classified. It is a 3,7-O-diglucoside 8-prenyl derivative of kaempferol. At present, Icariin has been the subject of numerous scientific investigations that have established its potential as a treatment for a wide range of cardiovascular ailments, including atherosclerosis, hypertension, stroke, heart attack, arrhythmia, heart failure, and hyperlipidemia. The protective potential of Icariin against a variety of cardiovascular diseases will therefore be the subject of this review article.

Keywords: Icariin, Atherosclerosis, Hypertension, Stroke, Heart attack, Arrhythmia, Heart failure, Hyperlipidemia.

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