FORMULATION AND EVALUATION OF DOLASETRON ORAL DISPERSIBLE TABLETS BY DIRECT COMPRESSION
Gaurav Takote*, Prof. V. G. Hule, Gopal Tekale, Shahid Shekh and Syed Aheteshamoddin
ABSTRACT
This work aims to create Dolasetron orally disintegrating tablets using direct compression and evaluate their properties. This dosage type is more suitable for pediatric and geriatric individuals. This technique is suitable for oral dispersion due to its convenience. Compared to all other excipient medicines, cross povidone exhibits high activity. Dolasetron along. Cross povidone resulted in over 95.34% drug release, outperforming SSG and cross carmellose. Cross povidone has a faster disintegration time than others. This study suggests that dolasetron may have significant anti-emetic properties.
Keywords: dolasetron, cross carmellose sodium, cross providone, sodium starch glyacolate, oral dispersible tablet, direct compression.
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