EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

TO STUDY PHARMACOLOGICAL ACTIVITIES OF LANTANA MONTEVIDENSIS

Prof. Harshada Shewale, *Pundalik Chandgude, Vaishnav Chavan, Pooja Choudhary, Preksha Bongirwar and Dhanshri Chaudhari

ABSTRACT

The pharmacological actions of Lantana montevidensis extracts were investigated across various domains, revealing promising therapeutic potential. Antifungal activity was observed in the essential oil extracted from L. montevidensis leaves, particularly when combined with fluconazole, enhancing its efficacy against Candida strains. Modulatory effects were demonstrated through the reduction of minimum inhibitory concentrations (MICs) of aminoglycoside antibiotics, suggesting a role in combating antibiotic resistance. Significant antioxidant activity was observed in both aqueous and ethanolic extracts, with the aqueous extract exhibiting stronger potency than ethanolic extract and ascorbic acid in scavenging DPPH free radicals. Cytotoxic effects on human leukocytes and erythrocyte membranes were noted, attributed to various compounds including gallic acid, catechin, chlorogenic acid, and quercetin. Furthermore, ethanolic extracts from L. montevidensis leaves and roots displayed notable antibacterial activity against multi-resistant bacterial strains, indicating potential therapeutic applications. Evaluation against L. donovani parasites and T. brucei brucei trypomastigote forms revealed promising antiproliferative activity, suggesting a role in combating parasitic infections. Overall, the findings highlight the diverse pharmacological potential of L. montevidensis extracts, warranting further investigation for therapeutic development.

Keywords: Antifungal activity, Antibacterial, Antioxidant, Antiprotozoal, Modulatory, Cytotoxic


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia