EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

EXPLORING MARINE SEAWEED-DERIVED PHYTOCONSTITUENTS AS POTENTIAL THERAPEUTIC AGENTS AGAINST MYCOBACTERIUM TUBERCULOSIS: A REVIEW

Rashith A.*, Dr. Sathiya Balan G., Keerthana T., Dr. Venkata Rathina Kumar T.

ABSTRACT

Globally, 7.5 million individuals were diagnosed with tuberculosis (TB). TB is an infectious pulmonary ailment instigated by Mycobacterium tuberculosis. This surge exceeded pre-COVID levels (7.1 million in 2019) by 16%, and surpassed 2023 figures by 28%. Although drugs like Rifampicin, pyrazinamide, Isoniazid, Ethambutal and streptomycin are used as first line drugs were used in the treatment and control of tuberculosis progression, cause hepatic disorder and drug resistance may occurs. Natural source such and plants and marine organisms possess various secondary metabolites acts against mycobacterium in vitro. The secondary metabolites act by various mechanisms to supress the growth of mycobacterium and also enhance the immunity. But yet to evaluated in humans and have to be standardised properly to ensure the safety and efficacy of the natural sources. This review will focus on the various marine seaweed derived phytoconstituents in recent year shown a promising activity against Mycobacterium tuberculosis. More research is required to get new moiety in the treatment of tuberculosis.

Keywords: Mycobacterium tuberculosis, Seaweed, GC-MS, Anti-tubucular and Marine natural products.

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