ACCURACY OF TWO-DIMENSIONAL TRANSVAGINAL SONOGRAPHY AS A DIAGNOSTIC TOOL OF INTRAUTERINE PATHOLOGY IN SUB-FERTILE PATIENTS IN COMPARISON WITH DIAGNOSTIC HYSTEROSCOPY
Agzail Saad Elhddad*
ABSTRACT
Background: endometrial pathologies are common in infertile women and adversely impact the reproductive outcome. Materials and Methods: this prospective study was conducted on 250 infertile women attending Albayda Fertility center/ Libya from January 2019 to July 2020. The diagnostic accuracy values of two-dimensional transvaginal sonography (2D TVS) in detection of intra-uterine lesions compared with a diagnostic hysteroscopy (DH) by receiver operating characteristic (ROC) curve analysis. Results: 2-D TVS had 70.2% sensitivity, 78.9% specificity, 70.9% positive predictive value (PPV), and 78% negative predictive value (NPV) for detection of endometrial pathology. Area Under the Receiver Operative Curve (AUROC) was; 0.745 (95% CI 0.681−0.810) for the accuracy of TVS compared to DH. Conclusion: transvaginal sonography had an acceptable accuracy for detection of uterine pathologies in infertile patients in comparison with diagnostic hysteroscope. Diagnostic hysteroscopy should be considered as an initial infertility workup before infertility treatment of patients with abnormal TVS findings.
Keywords: Infertility, intrauterine pathology, transvaginal sonography, diagnostic hysteroscope, AUROC.
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