FORMULATION, DEVELOPMENT AND EVALUATION OF PANDANUS ODORATISSIMUS EXTRACT CAPSULES DELIVERY SYSTEM AS AN ADVANCED PHYTOTHERAPY APPROACH FOR HEPATOPROTECTIVE

Prof. Dr. Mahmoud Mahyoob Alburyhi* and Prof. Dr. Amina El-Shaibany

ABSTRACT

The Pandanus Odoratissimus is medicinal plant widely distributed in Yemen; the objective of the present study was to prepare the methanolic extract of Pandanus Odoratissimus flowers as capsules delivery system which used for hepatoprotective activity. Use of medicinal plants and their products are almost doubled over the last decade in developing countries and the present trend of wide spread interest in alternative therapies is well known. Pandanus Odoratissimus is used in traditional systems of medicine to hepatoprotective activity. It was concluded that among the all formulations the formulation F2 is the best results of Pandanus Odoratissimus extract medicinal herbs capsules delivery system as an advanced phytotherapy approach for hepatoprotective according to the drug release was found to be 82% within 60 minutes.

Keywords: Pandanus Odoratissimus, Extract, Capsules, Medicinal herbs, Hepatoprotective activity, Phytotherapy.