EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

CHEMOVARIANT OF MELALEUCA QUINQUENERVIA (CAV.) S.T.BLAKE AND ITS ANTI-PATHOGEN ACTIVITY

Vasundhara M.*, Priyanka R., Sheetal R. Gujaran, Ashwini Jayaram and Radhika B.

ABSTRACT

Melaleuca species display chemotypic variations due to biotic and abiotic influence. Characterization of the chemical variant in a volatile oil is of prime importance for authentication of the sample and for evaluating its pharmacological activity. A study aimed at identifying a chemical variant of the essential oil extracted from Melaleuca quinquenervia, through Gas Chromatography-Mass spectrometry (GC-MS) analysis was conducted. E-Nerolidol, a sesquiterpene alcohol and this component was identified as the characteristic chemical variant of Melaleuca quinquenervia (Niaouli) was identified. Also, the essential oil of M.quinquenervia extracted on dry weight basis was screened against Oral and skin pathogens. The volatile oil displayed maximum growth inhibitory activity against dental and skin pathogenic strains. The potent antimicrobial activity exhibited could be due to the enhanced bacterial permeability and susceptibility to Nerolidol, a major component of M.quinquenervia essential oil.

Keywords: Niaouli oil, E-Nerolidol, Pathogenicity.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing