WEIGHT LOSS DIET STRATEGY IN AMELIORATING OBESITY: KETOGENIC DIET AND INTERMITTENT FASTING

G. Kinnera Ratna Sri*, M Ganga Raju, D. Gowthami, Y. Chenna Harshan Reddy, K. Lakshmi Sravani and P. Prasoona

ABSTRACT

Obesity is considered as one of the major global health concerns due to its significant increase in prevalence post COVID-19 pandemic. To combat obesity, several strategies were tried to minimise the use of marketed allopathic weight loss drugs among which dietary strategy is one of them. The ketogenic diet and intermittent fasting were the most well-known and extensively utilised weight loss plan. Ketogenic diet is composed mostly with fat and relatively lower carbohydrates. Intermittent fasting (IF) refers to the frequent periods of very limited or no calorie intake, which includes periods of intentional withdrawal from food and water consumption. Recently, intermittent fasting is gaining popularity and is consciously suggested as a potential therapeutic adjuvant. Few clinical research studies revealed the safety and pharmacological profile of ketogenic diet and intermittent fasting in promoting weight loss. In contrast, till now there are limited research studies on weight loss management post discontinuation of diet, which is more challenging now-a-days. Hence, the current review mainly attempted to address the mechanism by which the ketogenic diet and intermittent fasting produces weight loss and ameliorates obesity and associated metabolic disorders. However, it is necessary to continue research involving the consumption of ketogenic diet during intermittent fasting for its prolonged weight loss in obesity and associated metabolic disorders.

Keywords: Ketogenic diet, Intermittent fasting, low Carbohydrates and Metabolic disorders.