A COMPREHENSIVE REVIEW ON MULTIDISCIPLINARY APPROACH TO STUDY ANTIMALARIAL REMEDIES

Harsha Pawar*, Mayur Joshi, Dipti Masram and Nikita Dhake

ABSTRACT

Malaria is a serious health issue in tropical and developing countries in Sub-Saharan Africa, Southeast Asia, and India. Malaria is a leading cause of morbidity and mortality in many countries due to the failure of therapy and its rapid spread globally. Pharmacotherapy is the most prevalent therapeutic approach for the condition. The most significant challenge is the evolution of resistance to multiple drugs. In order to solve this issue, herbal medicinal herbs have been used for centuries worldwide. Plasmodium falciparum resistance to chloroquin has been observed in numerous countries. Mankind is blessed with a wide range of herbal plants for various ailments, with a lot of those useful for malaria treatment as well. This review discusses the safety and efficacy of herbal plants, since there is often insufficient data to ensure their quality, efficacy, and safety. Herbal remedies are not always safe and may include toxins due to their complex composition. Biotechnological research and genetic enhancement of herbal medicinal plants are becoming more prevalent. Utilizing high-quality, uniform raw materials over wild-harvested plants can improve the efficacy and safety of herbal medicines. This article focuses on multidisciplinary approaches for curing malarial threats in order to sustain healthy life.

Keywords: Herbal formulation, Plasmodium falciparum, Safety, Efficacy, etc.