EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

STUDY ON OUTCOME OF DIGOXIN USE IN HEART FAILURE PATIENTS

Mohamed Shakir, Farhan Rafeeque K. V., Mohammed Anaf V., Mohammed Usamahusnain, Dr. Jijo Joji*, Dr. Hanumanthachar Joshi K.

ABSTRACT

Aim and Objective: To compare the effectiveness and safety of the treatment with digoxin (exposed) and without digoxin (Unexposed) in heart failure patients. Materials and Methods: A prospective comparative study was carried out in Sri Jayadeva Institute of Cardiovascular Sciences and Research, Mysuru, Karnataka. Data were analyzed using SPSS, Excel and compared between group which had digoxin therapy and which do not have digoxin therapy for heart failure. Result: The study involved 200 patients, with 55.5% male and 44.5% female. In the exposed group (75 patients), the mean ejection fraction was 38.5, and in the unexposed group (125 patients), it was 40.4. Heart rate means were similar between the exposed (87.72) and unexposed (87.48) groups. Hospital stays were comparable, with a mean of 5.20 days in both groups. Sodium levels were slightly lower in the exposed group, while potassium levels were similar. Urea and creatinine levels also showed little variation between groups. Adverse drug reactions occurred in 32 patients from the unexposed group and 46 from the exposed group, with different severity levels. Conclusion: There is no difference between effectiveness in the exposed group and unexposed group, but the safety is more in unexposed group.

Keywords: Digoxin, Heart failure, Toxicity.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia