EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

HISTOPATHOLOGICAL SPECTRUM OF OVARIAN NEOPLASMS DIAGNOSED IN A NATIONAL CANCER INSTITUTE OF EASTERN INDIA

*Dr. Prachi Kukreja, Dr. Kaushambi Chakraborty, Dr. Srabanti Hajra and Dr. Saunak Mitra Mustafi

ABSTRACT

Purpose: Ovarian neoplasms are the seventh most common malignant tumours diagnosed worldwide in women.[1] Histopathological examination being mainstay of diagnosis determines the prognosis and behavior of tumour. We have conducted this study to explore more about the diversity of the primary ovarian tumours and correlate histomorphological features with immunohistochemistry (IHC) profile. Methods: A total of 53 cases of ovarian masses were studied. Histopathological features for each haematoxylin and eosin stained section were studied and further evaluation with immunohistochemistry was done. Results: A total of 53 specimens of ovarian masses were obtained from patients. On histopathological examination, majority of tumours were malignant with surface epithelial tumours being the most common histological type. In them High grade serous carcinoma was the most common subtype. The next common histological types were germ cell tumours and sex cord stromal tumours. Immunohistochemistry was done for all the cases. PAX8, WT1, p53 were positive in all cases of High grade serous carcinomas. Conclusion: Histopathological examination being the mainstay of diagnosis helps in early diagnosis, staging and determination of prognosis. Thus in our study we have tried to increase the understanding about the histopathological spectrum of ovarian neoplasms and their distribution according to the histological subtype.

Keywords: Ovary, Ovarian Neoplasms, Surface epithelial tumours, Serous carcinoma.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia