AMLODIPINE INDUCED GUM HYPERTROPHY IN A PATIENT OF MOTOR NEURON DISEASE

Ashish Sharma and Anupriya Sharma*

ABSTRACT

A 52 year old male patient known case of motor neuron disease was seen in outpatient department of Dentistry for progressive, painless hypertrophy of gums from last 3 months. On enquiring further he was on following drugs: Riluzole 50 mg Twice Daily & Amlodipine 5mg once daily. He was diagnosed hypertensive 6 months back and was started on amlodipine 5 mg once day PO. Three months post therapy he started developing enlargement of gums and occasional bleeding. On examination there was generalized pinkish, enlargement of gums involving both marginal and papillary gingiva around all the teeth, grade III gingival hypertrophy involving anterior maxillary and mandibular region. Oral hygiene was poor. There was no bleeding or discharge. Histopathology revealed gingival hyperplasia. Diagnosis of amlodipine induced gingival hyperplasia was made and patient was prescribed alternative antihypertensive along with oral hygiene. Patient refused for any surgical intervention for same.

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