EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

IBUPROFEN INDUCED HEMOGLOBINURIA- CASE REPORT

Dr. Prashant Wadagbalkar, Dr. Poonam Patel*, Dr. Swati V. Raipurkar, Dr. Amritesh Ranyan

ABSTRACT

Ibuprofen is the most commonly used NSAIDS for analgesic, anti inflammatory and antipyeritic effect. The major adverse reactions include the effects on the gastrointestinal tract (GIT), the kidney and the coagulation system. rarely NSAIDS can cause drug induced haemolytic anemia. We noted a case of hemoglobinuria in 5 yr old male child postoperatively after administration of ibuprofen. Diagnosis was made on the basis of exclusion of other drug, and review of literature. Suspected drug was stopped, following which urine colour changed to normal and hemoglobinurea subsided.The causality assessment as per the Naranjo algorithim established a â€Å¾probable‟ association between the hemoglobinurea and Ibuprofen (Naranjo Score 6).

Keywords: drug induced haemolytic anemia, hemoglobinuria, ibuprofen.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing