INFLUENCE OF ABO BLOOD GROUP ON COAGULATION PROFILE OF DONORS AT SABHA CENTRAL BLOOD BANK

Naser M. Alaasswad, Buthaina M. Khalfalah and Albashir M. Yhmed*

ABSTRACT

Introduction: Due to the effect of ABO blood groups on the level of factor VIII in plasma, it is also likely to effect on fibrinogen levels, thrombin generation time, and partial prothrombin time. Objectives: This study aims to evaluate the relationship between ABO blood groups and coagulation profile. Materials and Methods: This study was conducted on 152 blood donors who frequented the Sebha Central Blood Bank in the period of time (from February 15 to March 15). Prothrombin Time (PT), partial thromboplastin time (APTT) and fibrinogen were measured as well as determining the blood group for each sample, along with measuring weight, height and blood pressure. Results: The results showed that, there were no significant differences in age among the sample of the studied groups, and that none of the donors suffered from underweight. The results showed an increase in the level of APTT and PT in people with blood group AB compared to other blood groups, with a lower concentration of fibrinogen factor. Conclusions: The results of this study conclude that, people with blood group AB are less likely to have coagulopathies than other blood groups.

Keywords: ABO blood groups, Prothrombin Time, partial thromboplastin time, fibrinogen and coagulopathies.