VINCA ROSEA IN ANTICANCER ACTIVITY AND ITS FUTURE OUTCOMES
Anisha Kumari, Inder Kumar* and Kapil Kumar Verma
ABSTRACT
A subclass of medications known as vinca alkaloids is derived from the Madagascar periwinkle plant. They are derived organically from Catharanthus roseus G. Don, the pink periwinkle plant, and exhibit both cytotoxic and hypoglycemic properties. They have been employed as disinfectants, diabetic treatments, and high blood pressure treatments. The vinca alkaloids' ability to combat cancer makes them significant as well. In clinical application, vinblastine (VBL), vinorelbine (VRL), vincristine (VCR), and vindesine (VDS) are the four main vinca alkaloids. The United States has approved the usage of VCR, VBL, and VRL. Ten million people die from cancer each year, making it one of the most common illnesses in the world. Plant-based medications have emerged as viable possibilities for preventive chemotherapy in both affluent and underdeveloped countries. Alkaloids, among other
Keywords: Vinca, alkaloids, Catharanthus, anti-cancer, microtubule targeting agents, apoptosis.
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