ROLE OF HORMONAL STATUS IN THE DEVELOPMENT OF OVARIAN ENDOMETRIOMA

F. Sh. Oripova* and B. Z. Khamdamov

ABSTRACT

Background: Endometriosis affects approximately 10% (190 million) of women and girls of reproductive age worldwide. Access to diagnosis and timely treatment for endometriosis is important, but access to such services is limited in many countries, including low- and middle-income countries. Objective: The examination data of 87 patients with endometriotic ovarian cysts (ECOC) aged from 25 to 37 years were analyzed. Methods: The concentration of sex hormones (FSH, LH, prolactin, estradiol (on days 2-3 of the menstrual cycle) and progesterone (7 days before the start of the menstrual cycle) in peripheral blood serum was determined by enzyme-linked immunosorbent assay. Result: In patients with ovarian endometrioma, an increase in the level of estradiol and prolactin was found in comparison with the control group (p <0.001). The presence of ovarian endometriosis in patients does not have a negative effect on the state of the ovarian reserve. Conclusion: In patients with ovarian endometriosis, the biochemical parameters of the ovarian reserve do not have statistically significant differences in comparison with healthy patients.

Keywords: Ovarian endometrioma, sex hormones.