EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

HAEMOLYTIC ACTIVITIES AND ANTIDIABETIC EFFECT OF TERMINALIA ARJUNA AND EMBLICA OFFICINALIS

Amit Gupta* and Sushama R. Chaphalkar

ABSTRACT

Objective- To investigate anti-diabetic and haemolytic activity of aqueous stem bark extract of Terminalia arjuna and Emblica officinalis. Methods- Antidiabetic bioassay was done through estimation of blood counts, total cellular (i.e. proteins) and free haemoglobin content in diabetic blood plasma and also determined its haemolytic activity in human whole blood. Results- Overall, the results suggest that aqueous stem bark extract of Terminalia arjuna and Emblica officinalis showed anti-diabetic activity with respect to enhancement of granulocytes count and decrease in free haemoglobin content including total cellular content in diabetic human whole blood and plasma samples. Conclusions- Terminalia arjuna and Emblica officinalis, aqueous stem bark extract revealed the presence of bio-active constituents which are known to exhibit anti-diabetic activities.

Keywords: Terminalia arjuna; Emblica officinalis; aqueous stem bark extract; haemolytic; diabetic.

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