BENEFICIAL EFFECT OF VITAMIN-C ON MONOSODIUM GLUTAMATE INDUCED HEPATOTOXICITY IN RAT
Dr. Shyamal Kanti Das, *Dr. Soumendra Nath Karmakar and Bidisha Biswas
ABSTRACT
Present study has been undertaken to search the effect of vitamin-C on Mono Sodium Glutamate (MSG) induced hepatotoxicity in rat. MSG has impaired various parameters such as SGPT, SGOT, Alkaline phosphatase, total protein, serum SOD and catalase activity and the histological structure of liver significantly in all the experimental groups of animals. Significant improvement has also been noticed after applicatiuon of vitamin-C to the MSG treated animals of different doses along with improvement of histological status of liver.
Keywords: Monosodium Glutamate, antioxidant, Alkaline phosphatase, histology, necrosis and hepatotoxicity.
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