EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

SYNTHESIS, STRUCTURE AND BIOLOGICAL ACTIVITY OF NOVEL CURCUMIN THIOSEMICARBOZONE GOLD(III) COMPLEX: POTENTIAL ANTICANCER DRUG

Kalyani P., Subrahmanyam Naidu P. V.* and Prakash M. M. S. Kinthada*

ABSTRACT

Cancer harms the body when damaged cells divide into uncontrollably to form lumps or masses of tissue called tumors. Tumors that stay in one spot and demonstrate limited growth are generally considered to be benign. Cancerous cell manages to move throughout the body using the blood systems, destroying healthy tissue in a process called invasion. The anticancer potential of cur cumin is severely affected by its limited systemic and target tissue bioavailability and rapid metabolism. Various dietary chemo preventive agents, turmeric powder or its extract curcumin are broadly used as therapeutic preparations in Indian System of medicine. Cur cumin is a natural polyphenol. It is highly potential molecule capable of preventing and treating various cancers. In the present research work, we provide a summarized synthesis and biological activity of curcumin/curcumin thiosemicarbozone (curTSC) derivatives of Gold(III)complex. The use of these analogs for prevention of cancer tumor progression and treatments of human malignancies.

Keywords: Curcumin, CurTSC, anticancer, therapeutic, human malignancy.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing