( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Salman M.*, Venkatesh, Nagendra R., Mohammed Swaleh, Irfanulla Sharieff and Hanumanthachar Joshi


Probiotics have been said to assist healthy immunological and digestive systems. B.coagulans has become a focus of research due to its high temperature stable, highly viable, economical and Versatile in nature. The ultimate objective of the present research work is to incorporate B.coagulans strain into the gummies, which will benefit the human health. Gummies are formulated by Trio method. Optimization studies for ingredients was carried out to determine the concentration which is ideal for the preparation. Two different formulations were prepared with the help of Optimization data using sucrose, gelatin and pectin as the base for the preparation of gummies. All the prepared probiotic gummies were subjected to various evaluation parameters like pre- formulation studies, microbial analysis, nutritional facts and Stability data. The results of microbial analysis shows that viability of probiotic in gummy is not less than 500 million spores /gummy, total yeast and mold count is < 10 Cfu /gummy and Pathogen are absent in the formulations. Nutritional facts determines the content like Carbohydrate and Total Sugar content varied from 75.1% to 82.76% w/w and 65.4% to 79.91% w/w. Fat and protein in gummies with B.coagulans varied from 0.03 % to 0.78 % and 9.9 % to < 1%, respectively. The energy value of gummies varied from 338 kcal/100 g to 340 kcal/100gm. Short-term stability Studies indicate that there are no significant changes in physical characteristics, viable count, traces of yeast & mold and pathogens after 180 days of storage at 25±2⁰ C with 60±5% RH.

Keywords: B.coagulans, Viability, Nutritional facts, Stability studies.

[Full Text Article]




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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia