FORMULATION AND EVALUATION OF ORAL FAST DISINTEGRATING TABLET CONTAINING METRONIDAZOLE

Sindhu A.C.*, Harshitha B.M., Mahalakshmi A.S., Meghana H.C. and Vismaya C.J.

ABSTRACT

The drug delivery pharma industry is currently experiencing intense competition and quick evolution due to an ever-growing demand. One such novel and distinctive drug delivery method that is quickly gaining popularity in the realm of rapid dissolving technology is the fast-dissolving tablets (FDT). Due to oral route’s simplicity, adaptability, patient compliance, and precise dose, it is favored. For those with dysphasia a disorder that makes swallowing difficult, oral administration is not recommended. Additionally, oral delivery may not be the preferable method for many elderly and pediatrics patients. Oral disintegrating tablets (ODT) offer a helpful substitute in this regard. ODT tablets instantly (within30 seconds) breakdown upon contact with saliva, releasing the medication. Additionally, as it escapes first pass metabolism due to pre gastric absorption, this can be advantageous for medications with significant hepatic metabolism.

Keywords: oral disintegrating tablets, oral films, swallowing problems, orodispersable tablets, dysphasia.