A DOUBLE-BLIND CLINICAL TRIAL TO EVALUATE AND COMPARE THE EFFICACY OF FIVE DIFFERENT DENTIFRICES ON DENTAL HYPERSENSITIVITY: AN EIGHT WEEK STUDY

Dr. Sonia Datta*, Amit Sirdesai and Dr. Prasun Bandyopadhyay

ABSTRACT

Dentin Hypersentivity is growing in population with exposure to junk food, drugs and poor oral hygiene. A randomized double blind clinical trial was performed for comparative efficacy among five different toothpastes groups for dental hypersensitivity. The trial was performed with 175 (one hundred seventy- five) number of subjects in total divided into four groups of 35 each. The subjects were evaluated for instant relief (dab on study) after 60 sec of application and a long-term relief from dental hypersensitivity after usage for 8 weeks. Test group 1 (Potassium nitrate, Alum, Herbal extract, essential oils) &test group 2 (Potassium nitrate, Hydroxyapatite, Alum, Herbal extract, essential oils) showed a statistically significant improvement in long term dental hypersensitivity relief and a better efficacy in instant relief when compared to commercially available toothpaste 3 (Fluoride, Novamin based toothpaste)&4 (Control group 1 Fluoride based toothpaste & 2 Fluoride, Potassium nitrate-based toothpaste). However, there were no significant results obtained against Control group 3.

Keywords: Dentin Hypersensitivity, toothpaste, dentifrice, potassium nitrate, hypersensitivity.