EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

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Abstract

ROLE OF PRAKRUTI SAMA SAMAVETA AND VIKRUTI VISHAM SAMAVETA SIDDHANTA FROM AYURVEDA IN PHARMACOVIGILANCE

Dr. Pallavi Anand Korde*

ABSTRACT

In the age of modern technology, scientific advancements, consumer awareness and the advent of evidence based medicine, there is inadequate genuine clinical trial evidence supporting the efficacy and safety of Ayurveda drugs, except that this system is practised since hundreds of years. Another fact that supports it is the rarity of any adverse effect ever reported. Even the IEC guidelines for human trials take shelter under the fact that Ayurvedic drugs are time tested and require no evidence base of clinical safety data for approval of their use in humans. But this is a limitation which all along has interfered in acceptance of Ayurvedic medicines in developed world as a health care system. Further, a common misconception prevails among the masses and also a large population of practitioners is that Ayurveda drugs are safe and do not have any adverse reaction. Dravya is the entity which has been given with prime importance for its role in the prevention and treatment of different ailments. Generally Dravya act according to Rasa, Guna, Virya and Vipaka. In some other conditions the action of Dravya cannot be expressed or explained with the help of Rasa, Guna, Virya and Vipaka. Diseases will be manifested because of the involvement of single Dosha or in combination with other Dosha or all three together.In such conditions concept of Vikruthi Visama Samavetha is helpful. Prakruti Sama Samaveta and Vikruti Vishama Samaveta are the two Siddhant given by Acharya Charak while describing relation between Rasa-Dravya and Dosha-Vyadhi. This study is carried out with a view to know the applicability of this Siddhanta in understanding and prevention of ADR (Adverse Drug Reaction) and also to establish Pharmacovigilance in Ayurveda.

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