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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

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European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Syed Imtiaz Haider*, Shabana Simjee, Kauser Siddiqui, Ali Yasir Khanzada, Syed Mahmood Hassan and Syed Muhammad Imran


Dietary supplements have gained popularity as a means of enhancing nutritional intake and overall well-being. However, ensuring the safety of these supplements is essential to protect consumers from potential harm. Pre-clinical studies, often involving animal models, play a crucial role in assessing the chronic toxicity of dietary supplement capsules. These studies aim to mimic long-term human exposure to the supplement. The dietary supplement capsule (MDSC), „MENERGY‟, is formulated with a combination of vitamin B1, B6, Zinc, Selenium, and a blend of dietary herbs including Holy Basil (Tulsi), Tamarindus indicum, Curculigo orchioides, Anacyclus pyrethrum, Withania somnifera, and Panax ginseng extract. Previous studies have consistently shown the importance of the mentioned supplements in various aspects of male health, encompassing overall well-being, sexual desire, orgasm, erection, and mood. The purpose of this study was to evaluate the long-term safety of MENERGY, a dietary supplement capsule using vitamins, minerals, and traditional herbs in combination within specified limits. Study Methodology: The study is a non-clinical, experimental, control group to investigate the safety of „MENERGY‟ Dietary Supplement Capsules (MDSC) in a 90-day chronic toxicology experiment in male Wistar rats. The total of 36 Wistar (rats) were categorised in three groups in the experiment: a control group (CG), two treatment groups (TG-A and TG-B), and each group was given daily doses of MDSC of 30 mg/kg and 60 mg/kg, respectively. The study measured the rats' body weight, food and water intake, organ weights, tests to determine how effectively their liver and kidneys functioned, as well as their testicular, liver, and kidney histology. Results: The results showed that the body weight, food and water consumption, organ body weights, liver and kidney function tests, and histopathology of the liver, kidney, and testicles remained unchanged in all three groups. Moreover, spermatogenesis in the testicles showed a qualitative improvement in the treatment groups compared to the control group. Conclusion: The findings of this study indicate that „MENERGY‟ Dietary Supplement Capsules are safe and do not cause any gross pathology, liver or kidney damage, or histopathological damage to the liver, kidney, or testicles. Furthermore, the supplement may have a beneficial effect on spermatogenesis.

Keywords: Dietary Supplement, sexual dysfunction, non-clinical, Chronic Toxicology, Safety.

[Full Text Article]




    December issue has been successfully launched on December 2023.

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia