EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

FORMULATION DEVELOPMENT AND INVITRO EVALUATION OF TRANSDERMAL DRUG DELIVERY SYSTEM OF PROPRANOLOL HYDROCHLORIDE

Jagannadam Sai Sivachandu, V. Jhansi Priya Marabathuni* and Naidu Narapusetty

ABSTRACT

The purpose of the work was an attempt to develop a transdermal drug delivery system of Propranolol using three different polymer combinations i.e. CAB-PVP in different ratios. Total of 7 patches were prepared out of which the CAB-PVP patches were found to have better characteristics than the other two patches. From the in vitro release results observed, it was noticed that patches prepared using CAB-PVP proved to exhibit better release characteristics. The better results for the physicochemical parameters of CAB- PVP patches. Based on the results it concludes that the formulation F7 Shows better In vitro dissolution release studies it concluded that the concentration of CAB:PVP at 3: 7 ratio shows better results for formulation of the propranolol transdermal patches.

Keywords: Ttransdermal drug delivery, patches, in vitro dissolution.

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