ADVANCES IN GOUT MANAGEMENT: FOCUS ON PREVALENCE, IMAGING, AND TARGETED TREATMENT APPROACHES

Danyalakshmi P.G. S.*, Velmani C., Thaila R. and Dr. Senthil Raja M.

ABSTRACT

Academic and clinical settings have become increasingly interested in gout. This may be due to a number of factors. Gout prevalence and hyperuricemia have increased in developed countries, increasing its burden. According to recent literature, hyperuricemia is associated with gout and could also benefit cardiovascular health. Imaging techniques can be used to assess the extent of crystal depletion and urate deposition before clinical symptoms appear. As a treatment approach for various diseases, treating to target has become increasingly popular. Different targets have been recommended depending on disease burden and treatment stage. Efforts should be directed towards dissolving urate crystals in the tissues to prevent further symptoms and structural damage. It is recommended that gout and its associated comorbidities be treated as early as possible. A new imaging technique can also be used to assess the burden of urate deposition and the response to urate-lowering treatments. Urate crystal deposits are the final strategic goal of healthcare for patients with taste disorders.

Keywords: Gout, Uric acid, Urate crystals, Crystal deposition disease.