EFFECT OF ROSEMARY AND MYRTUS EXTRACTS COMBINATION ON ANDROGENETIC ALOPECIA: A COMPARATIVE STUDY WITH MINOXIDIL"
Mokhtar Abd Hafiz Al-Ghorafi*, Mahmoud Mahyoob Alburyhi and Fares M.S Muthanna
ABSTRACT
This study aimed to examine the hair regrowth effect of combining rosemary and myrtus extracts on androgenetic alopecia (AGA) and compare it to the commonly prescribed drug minoxidil. AGA is a widespread type of hair loss caused by dihydrotestosterone. Excessive testosterone in men is transformed into DHT, which attaches to androgen receptors in hair follicles and leads to hair thinning. The extracts of Rosmarinus officinalis and Myrtus communis leaves were extracted using 70% ethanol, microscopically screened, and investigated for phytochemical screening and antioxidants activity. The extracts were prepared as a 2% topical spray and tested on AGA-induced rabbits. The hair growth was measured on several days after starting application. The study showed that the combination of rosemary and myrtus extracts had a significant hair regrowth effect on AGA and was comparable to the effect of minoxidil .The results showed that the combination of rosemary and myrtus extracts significantly improved hair regrowth in AGA and had similar effects to minoxidil. Therefore, the combination of rosemary and myrtus extracts can be considered a safe and effective alternative treatment for AGA.
Keywords: Rosemary extract, Myrtus extract, Androgenetic alopecia, Hair loss Minoxidil, Comparative study.
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