( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Dr. Aditi Varshney Varma* and Dr. Ankur Varma


Background: Uteroplacental insufficiency is a major cause of perinatal mortality and morbidity in growth-restricted fetuses. Doppler ultrasound effectively measures the changes that sequentially appear in fetal arterial and venous systems and can predict adverse perinatal outcome. Venous changes in Doppler, when monitored, are preterminal events that can help frame delivery decisions in preterm infants. Objective: To determine Venous Doppler parameters in Intra uterine growth restricted fetuses (IUGR) and correlate with adverse perinatal outcome. Methods: 77 singleton pregnancies beyond 28 weeks of gestation, without fetal anomalies, that had estimated fetal weight below the 10th percentile for gestational age, were examined by Doppler ultrasound to record fetal cerebro-umbilical, Ductus venosus (DV) and umbilical vein (UV) indices. Fetal perinatal outcomes were noted. Results: The sensitivity, specificity, positive & negative predictive value of DV PI to predict IUGR in the present study was 58.3%, 100%, 100% & 40.5%. The sensitivity, specificity, positive & negative predictive value of DV PI to predict adverse perinatal outcome was 59.5%, 71.4%, 71.4% & 59.52% respectively. The incidence of IUD & neonatal mortality was higher in cases with abnormal DV PI (26%, 20%) than in cases with normal DV PI (4%, 4%) (p 0.026, 0.016), increasing with appearance of absence or reversal of a-wave in DV. 100% cases with pulsations in UV had intrauterine or perinatal demise. Conclusion: Abnormal DV PI and decreased UV velocity is a predictor of adverse perinatal outcome in the setting of abnormal fetal arterial Doppler. These parameters can be monitored in preterm infants to help frame delivery decisions.

Keywords: Ductus venosus, Umbilical vein, Doppler, Intrauterine growth restriction, perinatal mortality, adverse perinatal outcome.

[Full Text Article]



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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database