THE DIAGNOSTIC INTEREST AND STRATIFICATION OF NT-PROBNP IN THE CORONARY SYNDROME

Amrane Mounira, Boussouf Khaira, Attalah Salah*, Moufek Charafeddine, Abdelkebir Khadija, Touabti Abdelrezek

ABSTRACT

The risk of stratification plays an important role in the management of patients with ACS, and constitutes daily an aid to guide the strategy therapeutic. The natriuretic peptides, reflecting the ventricular dilatation and load conditions, could make a useful additional information. The natriuretic peptides are potent cardiac excess mortality markers in the SCA with or without extra-ST segment. Our objective is to evaluate the natriuretic peptide and several markers to identify patients scheduled to benefit from an early invasive strategy. This is a prospective study of 100 coronary hospitalized at the cardiology department for coronary syndrome. This is a prospective study of 100 coronary hospitalized in the cardiology department for coronary syndrome. The average age of coronary patients was 60.53 ± 12.32 years, with male sex predominance of 63.33%. 65.6% are coronary ST-. The average of NT-pro BNP rate is 2420.50 ± 4279pg / ml and it was related to the age and deterioration of renal function. In the study mono varies NT-proBNP is always associated coronary syndrome in the advancing age, at the injury of renal function, hyponatremia a reverse effect with obesity and the odds ratio is 2.35 (0.99 to 5.62) in the IDM. The NT-proBNP has great diagnostic and prognostic value in the stratification of the coronary syndrome.

Keywords: acute coronary syndromes, N-terminal pro-brain natriuretic peptide, hyponatraemia, obesity.