EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

ASSESSMENT OF PHARMACISTS' AND PATIENTS' KNOWLEDGE AND ATTITUDE TOWARDS IRRATIONAL USE OF CHLORDIAZEPOXIDE-CLIDINIUM BROMIDE COMBINATION IN KHARTOUM STATE

Malik Suliman Mohamed*, Ahazeej Hassan Hamid and Bashier Osman

ABSTRACT

This study was conducted to evaluate the knowledge and attitude of community pharmacists in controlling Chlordiazepoxide-Clidinium bromide (CC) dispensing and to assess the potential of irrational use of this combination product. Self-administered questionnaire was used as the study tool and distributed among 200 community pharmacist and 200 CC users. The majority of pharmacists [176/200 (88%)] were shown to dispense CC as OTC. Although the vast majority of respondent pharmacists [192/200 (96%)] mentioned frequent dispensing of CC for certain patients without prescription, but [196/200 (98%)] revealed no patient counseling regarding the presence of concomitant diseases and/or the use of other medications before dispensing CC. Concerning the pharmacist's knowledge about CC, only [60/200 (29.7%)] correctly mentioned the chemical group to which chlordiazepoxide belonged. Sedation was the most side effect of CC that reported by [114/200 (57%)] of pharmacist, followed by addiction [50/200 (25%)], constipation [48/200 (24%)] and tolerance [18 (9%)]. Regarding patients, most of them [141/200 (70.5%) reported purchasing of CC as OTC with the vast majority of them [195/200 (97.5%)] mentioned continued use beyond the prescribed course. The majority of patients announced the use of CC for 4-6 years. Only six (3%) women had used CC during pregnancy with three (50%) of them been aborted their pregnancies, two (33%) delivered children with thalidomide-like deformities and one (17%) had no problem.

Keywords: Chlordiazepoxide, Clidinium bromide, prescription, dispensing, patient counseling.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing