A SCIENTIFIC REVIEW ON ENTERIC COATED TABLET

Likitha C. S.*, Mamatha G.T.

ABSTRACT

Tablet coating is one of the oldest pharmaceutical processes still is existence. Coating is a process by which an essentially dry, outer layer of coating material is applied to the surface of a dosage form in order to confer specific benefits over uncoated variety. It involves application of a sugar or polymeric coat on the tablet. Enteric coated means a tablet or capsule or the other form of oral medication which is layered with a defensive coating. This coating is used to fortify the stomach from unwanted effects or detrimental effects of a medication. Most enteric coatings work by presenting a coated surface that is stable at the highly acidic pH found in the stomach, but breaks down rapidly at a less acidic (relatively more basic) pH . Materials used for enteric coatings include CAP, CAT, PVAP and HPMCP. So in order to obtain a gastro resistant drug it should have enteric coating and suitable polymers for the dosage form. Different polymers were used in enteric coating like cellulose acetate phthalate, polyvinyl acetate phthalate, hydroxyl propyl methyl cellulose. The present review describes enteric coating, their ideal properties, various polymers used, methods of manufacturing and evaluation of enteric coated tablets study provides an overview of the recent advances that have taken place in this arena.

Keywords: Enteric coated tablet, Evaluation, Ideal Properties, Mechanism and Methods of enteric coated tablets.