LOW DOSE INTRAVENOUS IMMUNOGLOBULIN FOR ACUTE IMMUNE THROMBOCYTOPENIC PURPURA IN CHILDREN

Mustafa Al Haji M.D*, Alaa Al Tawalbeh, MD and Ahmad Sharadgah MD.

ABSTRACT

Immune thrombocytopenia (ITP) is a common disease in the pediatric age group. Acute ITP is diagnosed in children who present with a bleeding disorder with isolated thrombocytopenia in the absence of other causes.[1] It is a self-limiting autoimmune disorder against platelets leading to its destruction in the spleen.[2] Regardless of its self-limiting nature, platelet counts often are very low with the possibility of spontaneous bleeding making the treatment imperative. Most experts agree that the intervention is indicated if platelet count is less than 20,000/micl.[1] immunoglobulin is considered the most effective treatment in the management of acute. IVIG at 2 grams per kg body weight was shown to be more effective to high dose prednisolone and to no intervention.[2,3] ITP has a lot of possible adverse reactions as well as financial burdens. The purpose of this retrospective analysis is to find out the effectiveness of low dose IVIG in the context of acute ITP management.

Keywords: .