NANOSUSPENSIONS: A COMPREHENSIVE REVIEW

Sana Sultana*, Shahid Mohammed and Risha Miskan

ABSTRACT

The study of science, engineering, and technology at the nanoscale, where particle sizes range from 1 to 100 nm, is known as nanotechnology. It is a component of nanotechnology. Drug particles stabilised by surfactants and stabilisers colloidally scatter at submicron sizes in nano-suspensions Drugs that are inefficient in lipidic or aqueous environments may be made more soluble. By using nano-suspensions, which speed up the time it takes for the active ingredient to reach its peak plasma concentration. By addressing the issues of low solubility and bioavailability and changing the pharmacokinetics of the drug, nano-suspensions enhance both its safety and effectiveness. The challenges posed by these traditional methods for improving solubility and bioavailability are overcome by nanotechnology. The field of nanotechnology focuses on tiny particle in the 10- to 9-metre region of the nanoscale. The nano-suspensions are thoroughly explained in the article. In nano-suspensions, pure, insufficiently water-soluble drugs are suspended without any matrix material, are used to increase solubility.

Keywords: Bioavailability, Solubility improvement, Site-specific drug delivery, Nanotechnology, Nano-suspensions, Safety and Efficacy.