A REVIEW OF POLYCYSTIC OVARIAN SYNDROME: IMPLICATIONS FOR NON-COMMUNICABLE DISEASES
Irum Ismail, Rahman Gul*, Safia Mengal, Ghulam Farooq, Kashmala Khan, Abdul Qadir and Wajid Khan
ABSTRACT
The review article provides a comprehensive overview of polycystic ovarian syndrome (PCOS) and its connection with various non-communicable diseases. The article discusses the clinical features, diagnostic criteria, genetic predisposition, and environmental triggers of PCOS. It highlights the extensive risk of metabolic issues, with dyslipidemia and type 2 diabetes, as well as abdominal obesity metabolic syndrome. The review also explores the association of PCOS with non-alcoholic fatty liver illness, hypertension, coagulation disorders, and increased cardiovascular risk. Furthermore, the article discusses the potential link among PCOS and ovarian, endometrial, and breast cancers, as well as the higher prevalence of depression among women through PCOS. The conclusion emphasizes the importance of lifestyle modifications and further research to better understand and manage PCOS.
Keywords: PCOS, androgen, insulin, animal models, cardiovascular diseases, depression, obesity, lifestyle.
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