A CASE OF HURTHLE CELL ADENOMA OF THYROID: CASE REPORT AND LITERATURE REVIEW

Samia A. Bokhari, Nouf Abdul Karim Al Shehri, Lama Khaled Arfaj, Areej A Bokhari, Patan Murthuza Khan*, Al Hussain Abdullah Al Sharif and Wala Abdul Razzak Felemban

ABSTRACT

Background: Both benign (Hürthle cell adenoma) and malignant (Hürthle cell carcinoma) Hürthle cell neoplasms are possible. Hürthle cell carcinoma, which makes up 5% of all differentiated thyroid carcinomas, is an uncommon tumor. Due to cytomorphologic characteristics that overlap with other follicular-patterned lesions, thyroid follicular adenoma and carcinoma, as well as Hurthle cell adenoma and carcinoma can be difficult to diagnose cytologically. As a result, it is exceedingly challenging to distinguish between these two entities before surgery, and this is only made feasible by the pathohistological analysis of the removed thyroid tumor. Case study: A 39 year old female. Presented to our clinic with thyroid nodule since 7 years With suspicious of follicular neoplasm in FNA biopsy, on march 2022 she underwent total thyroidectomy. The sample of pathology showed hurthal cell adenoma. Conclusion: Only a histological assessment could clearly distinguish between Hürthle cell adenomas and Hürthle cell carcinomas. Patients with cytologically confirmed Hürthle cell tumors should proceed with Total thyroidectomy especially if the tumor is greater than 1 cm.

Keywords: Hürthle cell adenoma, Thyroid, Oncocytic, Rare, Aggressive tumors.