SARCOPENIA AS MUSCLE ATROPHY BY AGING

*Prof. Dr. Dhrubo Jyoti Sen

ABSTRACT

Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility, diminishes quality of life, and can lead to fall-related injuries, which require costly hospitalization and extended rehabilitation. It is the decline of skeletal muscle tissue with age, is one of the most important causes of functional decline and loss of independence in older adults. It represents a loss of muscle strength and mass in older individuals and is a major determinant of fall risk and impaired ability to perform activities of daily living, often leading to disability, loss of independence and death. It affects your musculoskeletal system and is a major factor in increased frailty, falls and fractures. These conditions can lead to hospitalizations and surgeries, which increase the risk of complications including death. Focusing on muscle strength as the key component of sarcopenia, the aim of this overview was to evaluate its links to nutrition, both to variation in habitual diets in older populations, as well as considering supplementation effects in trials.

Keywords: Leucine, Ursolic acid, Vitamin D, Vitamin E, Omega-3 fatty acid, DHEA.