EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

DRUG INDUCED ACUTE SEVERE NECROTISING PANCREATITIS

Nishi Somarkutty*, Bincy Charley, Bobby Abraham, Chepsy C. Philip and Deepak K. Johnson

ABSTRACT

Acute necrotizing pancreatitis is a life threatening form of acute pancreatitis and is characterised by inflammation associated with pancreatic parenchymal necrosis or peripancreatic necrosis. After alcohol and gallstones are ruled out, drug-induced pancreatitis (DIP), which accounts for up to 5% of all acute pancreatitis cases, is the third most common cause of acute pancreatitis. Drug-induced pancreatitis affects around 5-80 persons worldwide per 100,000. In addition to youngsters, the elderly, and those with inflammatory bowel disease, DIP has been observed to be greater in people who are immunosuppressed. Didanosine, Azathioprine, Valproic acid, Mercaptopurine, Mesalamine, Tetracycline, Steroids, Furosemide, etc. are the medications most frequently documented to cause acute pancreatitis (those in which reaction reappeared after challenge dechallenge-rechallenge). However, other drugs like Rifampin, Erythromycin, Octreotide and several others have also been known to cause acute pancreatitis. In this case report we present the case of a 17 year old female patient who developed acute severe necrotizing pancreatitis following treatment with Azathioprine, Eltrombopag and Prednisolone for Immune thrombocytopenic purpura (ITP).

Keywords: Eltrombopag, Azathioprine, Prednisolone, Acute Necrotizing Pancreatitis, Immune Thrombocytopenic Purpura.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia