EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

CEFTAZIDIME-AVIBACTAM INDUCED BICYTOPENIA: A CASE REPORT

Neha Susan Vinu*, Nikhil M Sunny and Dr. S. K. Mathew

ABSTRACT

Ceftazidime-avibactam is one of the most commonly used third generation cephalosporin antimicrobial agent, which has action against gram negative susceptible and other non susceptible pathogens. Several adverse effects have been reported with ceftazidime- avibactam. In this case report, we discuss one of the growing haematological adverse effects of Ceftazidime avibactam- bicytopenia in which the platelet count had risen within 24 hours after withdrawing the drug. Cases on ceftazidime-avibactam induced bicytopenia are under reported. The use of such drug for gram negative susceptible pathogens are increasing worldwide, hence these life-threatening adverse effects should be borne in mind during every treatment.

Keywords: Ceftazidime -Avibactam, Bicytopenia, Gram Negative Organism, Pseudomonas aeruginosa.

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