CONSTITUENTS OF THE CHEMICAL HEARTWOOD OF BERBERIS ARISTATA, AERIAL PARTS OF CENTELLA ASIATICA AND FRUITS OF CORIANDRUM SATIVUM

Shahnaz Sultana, Mohammed Ali* and Showkat Rasool Mir

ABSTRACT

Berberis aristata DC. (family Berberidaceae) is an erect, evergreen, spiny, woody shrub. Centella asiatica (L.) Urban (family Apiaceae) is a small slender perennial, spreading herb. Coriandrum sativum L. (family Apiaceae) is an erect, many-branched, small, glabrous, bushy, annual herb. The heartwood of B. aristata , aerial parts of C. asiatica and fruits of Coriandrum sativum are used to treat various diseases. This study was planned to isolate phytoconstituents from these plant materials and to characterize their structures. The heartwood of B. aristata afforded n-docosane (1), β-sitosterol (2) and 1-hexacosanyl benzoate (3). The aerial parts of C. asiatica furnished two new fatty acid esters identified as octacosan-1-olyl (Z)-octadec-9-enoiate (n-octacosanyl oleate, 4), a new fatty acid ester and docosan-1-olyl tetracosanoate (n-docosanyl lignocerate, 5). The fruits of Coriandrum sativum produced 13α-hydroxystearic acid (6). The structures of isolated phytoconstituents were established on the basis of analysis of spectral data and chemical means.

Keywords: Berberis aristata heartwood, Centella asiatica aerial parts, Coriandrum sativum fruits, Phytoconstituents, Isolation, Characterization.