EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

DRUG UTILIZATION EVALUATION OF ANTIBIOTICS IN PEDIATRIC PATIENTS OF A TERTIARY CARE HOSPITAL IN CALICUT

Sahithya E. V., Sharafiyya, Shifanath A., Shareefa Banu K. P., *Sanjay Sreekumar K., T. Siraj Sundaran and G. Babu

ABSTRACT

Background: Determining the trends of drug utilization evaluation of antibiotics for pediatrics help to provide information of prescribing pattern to all health care professions and that will prompt judicious use of antibiotics. Objectives: To evaluate prescribing pattern of antibiotics in pediatrics and to check its rationality. Methodology: A retrospective observational study pattern was followed for the study at PVS Hospital (P) Ltd, Calicut. The case sheets and prescription of age group 1 - 16 years were collected. The antibiotic and their doses prescribed were compared with the standard guidelines for appropriateness and rationality. Results: Out of 135 pediatric patients 60% were male and 40% were female with 81% of patients in the age group 0-5 years. As per the study respiratory tract infection was the major cause of hospitalization in pediatric that covered 49% of all the clinical conditions encountered. Among the antibiotics prescribed 83% were cephalosporin with 3rd generation cephalosporin being the commonly prescribed one. The study showed 65% patients were prescribed with antibiotic monotherapy and 35% with antibiotic combination therapy with amoxclav being the mostly prescribed antibiotic combination. It was also found that 64.5% of antibiotics were prescribed in the injection form. Prevalence of antibiotic sensitivity test was found to be 0.74%. Conclusion: Antibiotics are frequently prescribed in pediatric population without proper antibiotic sensitivity testing. The clinical pharmacy department should give more emphasis in optimal prescription of antibiotics with proper follow up on whether the pediatrics follows the therapy to ensure the outcome of therapy.

Keywords: Drug utilization evaluation, pediatrics, antibiotics, standard treatment guidelines, Gyssen’s rationality categorization.

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