TRANSDERMAL DRUG DELIVERY SYSTEM: AN UPDATED REVIEW

Nilam R. Nehare*, Pooja E. Waware, Mona D. Gajbhiye, Pooja D. Bhandare and Puja B. Durge

ABSTRACT

Transdermal administration has an advantage over injectable and oral methods because it increases patient compliance and avoids first-pass metabolism, respectively. Therapeutic agent delivery via topical means has various benefits over more intrusive and traditional medication delivery techniques like oral ingestion.[24] Compared to other dosing methods, Predictable blood level profiles, controlled drug release into the patient, fewer systemic side effects, and occasionally higher efficacy are just a few advantages of transdermal medicine delivery. The primary goal of transdermal drug delivery systems is to deliver medications into the bloodstream through the skin at a predefined rate with little variation between and within individuals. This article gives a general review of the several types of transdermal patches, their preparation techniques, and their physicochemical methods of assessment.

Keywords: TDDS, Transdermal patches, Diffusion process, Topical drug delivery system.