EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

PREVALENCE OF PHOTOTHERAPY INDUCED HYPOMAGNESEMIA IN TERM NEWBORNS WITH JAUNDICE

*Dr. Raveena Rathod, Dr. Gullapudi Prakash and Dr. Sanjeev Chetty

ABSTRACT

Introduction: Hyperbilirubinemia(Jaundice) is common problem in neonates, is seen in about 60% of term neonates in first week and 80 % of preterm neonates. Phototherapy is the safest and commonly used treatment modality in neonatal jaundice. This study is aimed to measure the serum magnesium levels in neonates with hyperbilirubinemia before and after phototherapy to know the prevalence of phototherapy induced hypomagnesemia in term neonates. Methodology: This cross-sectional study was conducted on 100 term neonates with jaundice and receiving phototherapy, attending and admitted in Navodaya Medical College Hospital and Research Centre, Raichur. Study included full term neonates with unconjugated hyperbilirubinemia requiring phototherapy. Patient data was recorded in structured profoma. Serum bilirubuin level and magnesium level were sent before starting phototherapy and 48 hours after starting phototherapy. Results: There was statistically a significant difference in relation to magnesium level and ionized magnesium level before phototherapy and after phototherapy. No significant association was found between birth weight, postnatal age, mode of delivery, blood group incompatability and effect of phototherapy on s.magnesium level. Conclusion: The present study concludes that the phototherapy leads to a decrease in the levels of magnesium. The mean serum magnesium level reduced significantly after phototherapy in neonates with hyperbilirubinemia irrespective of age, sex, birth weight and mode of delivery. Phototherapy decreases bilirubin proportionately to IMg, implying that bilirubin and Mg levels in the blood have a positive relationship.

Keywords: Hyperbilirubinemia; Phototherapy; Hypomagnesemia; Magnesium; Bilirubuin.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia