EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

EVALUATION OF ALCOHOLIC CONSUMPTION ON SERUM URIC ACID, UREA, AND CREATININE LEVELS

Yahia Sayed Mohamed, Suhair A. Ahmed, Siddig B. Mohamed, AbdElkarim A. Abdrabo*

ABSTRACT

Background: Several metabolic changes occurs in humans’body duo to alcoholic consumption which may lead to changes in biochemical substance such as uric acid, urea and creatinine. Objective: The objective of this study was to evaluate and compare serum uric acid, urea and creatinine in alcoholic and non-alcoholic abuse. Methodology: This is descriptive case control study carried in Khartoum state. One hundred (100) apparently healthy males (50 Alcoholic abuse and 50 non- alcoholic abuse) serum uric acid, urea and creatinine were estimated using endpoint and kinetic methods and established mathematical analysis. Results: The (mean ±SD in mg/dl) of serum uric acid urea and creatinine in alcoholic abuse respectively were (7.8 ±1.06, 39.5 ±6.9, 1.01 ±0.21) while the (mean ±SD) of serum uric acid, urea and creatininein non-alcoholic abuse respectively were (5.2 ±0.8, 32 ±7.2, 0.8 ±0.2)The results showed that there was significant difference in the uric acid between the two groups (P value < 0,005) there was no significant difference in the urea between the two groups (P Value > 0.005). There was no significant difference in the creatinine between the two groups (P value >0.005). Conclusion: The result was concluded that there was significant increase in serum uric acid in alcoholic abuse groups (value 0.00). While urea and creatinineremainedunchanged and no significant difference between alcoholic and non-alcoholic abuse (P value 0.077 and 0.64 respectively).

Keywords: serum uric acid, urea and creatininein.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia