EVALUATION OF ALCOHOLIC CONSUMPTION ON SERUM URIC ACID, UREA, AND CREATININE LEVELS
Yahia Sayed Mohamed, Suhair A. Ahmed, Siddig B. Mohamed, AbdElkarim A. Abdrabo*
Background: Several metabolic changes occurs in humans’body duo to alcoholic consumption which may lead to changes in biochemical substance such as uric acid, urea and creatinine. Objective: The objective of this study was to evaluate and compare serum uric acid, urea and creatinine in alcoholic and non-alcoholic abuse. Methodology: This is descriptive case control study carried in Khartoum state. One hundred (100) apparently healthy males (50 Alcoholic abuse and 50 non- alcoholic abuse) serum uric acid, urea and creatinine were estimated using endpoint and kinetic methods and established mathematical analysis. Results: The (mean ±SD in mg/dl) of serum uric acid urea and creatinine in alcoholic abuse respectively were (7.8 ±1.06, 39.5 ±6.9, 1.01 ±0.21) while the (mean ±SD) of serum uric acid, urea and creatininein non-alcoholic abuse respectively were (5.2 ±0.8, 32 ±7.2, 0.8 ±0.2)The results showed that there was significant difference in the uric acid between the two groups (P value < 0,005) there was no significant difference in the urea between the two groups (P Value > 0.005). There was no significant difference in the creatinine between the two groups (P value >0.005). Conclusion: The result was concluded that there was significant increase in serum uric acid in alcoholic abuse groups (value 0.00). While urea and creatinineremainedunchanged and no significant difference between alcoholic and non-alcoholic abuse (P value 0.077 and 0.64 respectively).
Keywords: serum uric acid, urea and creatininein.
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