THE SIGNIFICANCE OF A TUMOR MARKER IN THE SCREENING EXAMINATION OF CHILDREN LIVING IN UNFAVORABLE REGIONS

*Jiemuratova G. K., Ahmedjanova Z. I., Kalandarova A. N. and Kadyrova A. M.

ABSTRACT

This article presents an analysis of the structural characteristics of malignant neoplasms in children and investigates the influence of environmental factors originating from the Aral Sea region on the adaptive mechanisms of the body. Notably, there has been a significant rise in the incidence of oncological diseases among children and adolescents, which, according to researchers, may be attributed to the exposure to salt-pesticidal mixtures. These observations highlight the potential use of HE4 as a novel oncomarker in screening studies, providing a rationale for conducting comprehensive examinations of organs or organ systems that are at risk of cancer.

Keywords: tumor marker, incidence, children, risk factors, Aral Sea region.