( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57



Tembe Estella Fokunang, Mbong Annih Grace, Manju Evelyn Bih, Lem Edith, Dobgima John Fonmboh, Ngo Valery Ngo6, Ngum Samuel, Ben Enoluomen Ehigiator, Lovet Benyella Fokunang, Zelinjo N. Igweze, Tih Pius Muffih and Charles Ntungwen Fokunang*


The there is a global strong interest to improve the therapeutic value of drugs through the improvement of bioavailability of many active compounds. The co-administration of active pharmaceutical agents from natural products with improved absorption activities has gained great interest in oral drug delivery. Many phytochemicals from medicinal plants have shown their capacity to improve the bioavailability of co-administered drugs by inhibiting efflux pumps or oxidative metabolism, and influencing the intestinal brush border membrane. Some of these known natural bioactive compounds include quercitine, genistein, glycyrrhizin, nitrile glycosides, sinomenine, piperine, naringin, and many others under study. The status of human nutrition also constitutes an important determinant of the quality of life, morbidity, and mortality. With an increase in nutraceutical potential of foods and food supplement, supported by the claims of health benefits, researchers have strong advocacy awareness and accountability for regulatory compliance of the therapeutic and toxicologic effect of phytochemicals, nutritional supplements and foods. To address the challenges of safety and quality of phytochemicals, an understanding of bioavailability of these products becomes evident. For a better increasing understanding of nutraceuticals, it is important to have an increased understanding of nutrition and therefore physicians, allied health practitioners, patients, and public health policy makers have more sensitization to better understand the basis for efficacy and safety of nutritional supplements and foods. Novel delivery systems that modulate the pharmacokinetics of existing drugs, such as nanoparticles, cyclodextrins, niosomes, liposomes, could be exploited to enhance the delivery of bioactive compounds and enhanced bioavailability at target sites. This review gives an insight into bioavailability in natural products phytochemicals as one of the factors that can enhance significantly the pharmacokinetic profile of a drug. This paper discusses the improvement of drug bioavailability exhibited by natural compounds from plants, some of the delivery approaches that have already made an impact by either delivering a drug to target tissue or increasing its bioavailability by many fold changes.

Keywords: Bioavailability, phytochemicals, pharmacokinetics, natural products, food, toxicology, microbiome, dietary intake, metabolism.

[Full Text Article] [Download Certificate]


  All Since 2019
 Citation  3086  2560
 h-index  18  17
 i10-index  64  44



  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 July 2024 Issue has been Published, Kindly check it on


    JULY 2024 issue has been successfully launched on JULY 2024.

  • EJPMR New Impact Factor

    EJPMR Impact Factor has been Increased to 7.065 for Year 2024.

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.


  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia