EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

FLAVONE C-GLYCOSIDE AND A NEW TANNIN ISOLATED FROM THE LEAVES OF NEOCARYA MACROPHYLLA (SABINE) PRANCE (CHRYSOBALANACEAE) USING CENTRIFUGAL PARTITION CHROMATOGRAPHY

Diara Diatta, Oumar Sambou, Philomène Akoua Yao-Kouassi, Isabelle Lachaise, Michael Rivard, Charlot Diatta, Firmin Sylva Barboza, Guata Yoro S. Y. and Abdoulaye Gassama*

ABSTRACT

Neocarya macrophylla (sabine) Prance is a plant of the traditional senegalese pharmacopoeia. Its leaves are used in the treatment of various diseases. The phytochemical investigation of its leaves resulted in the isolation of the new tannin (1), 1-O-galloyl-6-O-lutéoyl R-glucose (2) and Isoorientine (3). Their structures were isolated and characterized by using a combination of centrifugal partition chromatography (CPC), NMR (1D and 2D) spectroscopic and mass spectrometry (ESI-MS) analyses, as well as by its comparison with literature values. This study constitutes the first phytochemical examination of the leaves of N. macrophylla.

Keywords: Neocarya macrophylla, Leaves, Centrifugal Partition Chromatography, Preparative Chromatography, Tannin, flavone C-glycoside, NMR (1D and 2D).

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